Oleyl Alcohol | High-Purity Oleyl Alcohol for Pharmaceutical & Cosmetic Applications

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Oleyl Alcohol | High-Purity Oleyl Alcohol for Pharmaceutical & Cosmetic Applications
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Oleyl Alcohol is a fatty alcohol widely used in pharmaceutical, cosmetic, and personal care formulations. Explore its properties, applications, and supply options for industrial use.

Oleyl Alcohol

Introduction:

Oleyl Alcohol, also known as 9-Octadecen-1-ol, is an unsaturated fatty alcohol with a long carbon chain and one double bond. It is typically a colorless to pale yellow oily liquid.

Due to its excellent emollient, lubricating, and formulation properties, Oleyl Alcohol is widely used in pharmaceutical, cosmetic, and personal care industries.

It can serve as an emollient, emulsifier, thickening agent, and formulation ingredient in various products, including creams, lotions, ointments, and other specialty formulations.

Oleyl Alcohol

Name: Oleyl Alcohol

M.F.: C18H36O

M.W.: 268.5

CAS No.: 143-28-2

Packaging: 5kg/bottle*2bottles/carton; 5kg/bottle*4bottles/carton

Quality Standard: USP43-NF38; EP10.0;BP.

Appearance: Colorless to pale yellow clear oily liquid with a faint special odor and a plain taste.

It is soluble in ethanol, ether, isopropanol and light mineral oil, insoluble in water.

Application: 

A mixture of saturated and unsaturated long-chain fatty alcohols. The HLB value is 14, making it a widely used surfactant.

Oleyl Alcoho is a highly purified lipid-based solubiliser and skin penetration enhancer that acts as a wetting agent and active dispersant in topical creams and ointment applications.

Oleyl Alcoho is a lipophilic enhancer that promotes skin penetration by means of bilayer disruption and disordering. It assists the percutaneous absorption of water-soluble and oil-soluble drugs by means of partial leaching of the epidermal lipids. The bilayer architecture of the stratum corneum lipids is disorganised by the introduction of phase separation and direct disruption of a proper lamellar arrangement. This results in the improvement of the skin’s reception for transdermal and transfollicular penetration. The proprietary Super Refining process removes impurities without altering the chemical composition of the excipient. This reduces the potential for adverse interactions between the excipient and the API, enhancing active stability and efficacy.

ApplicationFunctionExample
PatchMoisturizing agentPenetrating agentOil phase matrix 
Cosmetic Cream, lotion, gel
Ointment Pyrrolimus Cream 1%:Each gram of 1% ELIDEL cream contains 10 mg of Pyrrolimus, with a white cream base consisting of benzyl alcohol, cetyl alcohol, citric acid, monoglycerides and diglycerides, oleyl alcohol, propylene glycol, sodium cetyl sulfate, sodium hydroxide, stearyl alcohol, triglycerides, and water.

Incompatibility: Incompatible with strong acids and oxidants. It can dissolve some rubbers and swell them.

Safety: This product has low toxicity but should not be taken orally, and has a slight tissue irritation.

Storage: This product should be preserve in well-filled, tight containers, and store at controlled room temperature.


FAQs

Q1: What is Oleyl Alcohol?

Oleyl Alcohol is an unsaturated fatty alcohol derived from oleic acid-related fatty materials. It is widely used in pharmaceutical, cosmetic, and personal care formulations.


Q2: What is the CAS number of Oleyl Alcohol?

オレイルアルコールのCAS番号は143-28-2です。


Q3:オレイルアルコールは何に使用されますか?

オレイルアルコールは、化粧品、パーソナルケア製品、医薬品、および工業用途において、保湿剤、製剤成分、特殊脂肪アルコールとして一般的に使用されています。


Q4:オレイルアルコールは化粧品の処方に適していますか?

はい。オレイルアルコールは、クリーム、ローション、ヘアケア製品など、化粧品やパーソナルケア製品の処方に広く使用されています。その適合性は、製品のグレードと処方要件によって異なります。


Q5:オレイルアルコールの外観はどのようなものですか?

オレイルアルコールは通常、無色から淡黄色の油状液体です。その外観は、純度や製品仕様によって異なる場合があります。


Q6:オレイルアルコールは水に溶けますか?

いいえ。オレイルアルコールは水にはほとんど溶けませんが、多くのオイルやオーガニック配合成分と相性が良いです。


Q7:オレイルアルコールはどのような産業で使用されていますか?

主な応用産業としては、医薬品、化粧品、パーソナルケア製品、特殊化学品製造などが挙げられる。


Q8:オレイルアルコールはどのように保管すべきですか?

通常は、密閉容器に入れ、高温多湿を避け、換気の良い涼しく乾燥した場所に保管してください。供給元の安全データシート(SDS)および保管に関する指示に従ってください。


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